16 year old male came to casualty with c/o fever

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A 16 year old Male came to casualty with 
C/O fever since 4 days
vomitings 6-7 episodes per day since 4 days, bilious, food as particles
C/O Generalised weakness, bilateral leg pain since 4 days
C/O loose stools 4-5 episodes per day,liquid in consistency since 3 days
Decreased urine output since 3 days
Epigastric pain since morning

Pt was apparently asymptomatic 4days back then on 17/10/22 night after consuming alcohol he developed fever, high grade, intermittent not associated with chills and rigor  Continued for 4 days rel?
He had 7-8 episodes of vomitings since 4 days which is bilious, projectile type
He has generalised weakness with bilateral leg pain since 4 days
He has 4-5 episodes of loose stools(liquid consistency) per day for 3 days
 Decreased urine output since 3 days
Epigastric pain since morning,dull aching type,not radiating type
No H/O burning micturition,headache
Addictions: alcohol since 6 yrs(occationally-2,3 times per week
cannabis since 6yrs(1-2smokes per day)
tobacco smoking since 6yrs(daily 10 per day)
K/C/O epilepsy since 4 yrs (not on regular since 2yrs medications)
N/K/C/O HTN,DM,TB,asthma,Thyroid,CVA,CAD
Occupation:fast food master(stopped studying at 7th class(4 years back))
Sleep-inadequate
Mixed diet
General examination:
No pallor
No icterus  
No cyanosis 
No clubbing 
No generalized oedema

Vitals:  
On admission 
Pt is Conscious, coherent, cooperative 
Temp: 99.1F
PR: 98BPM
RR: 16Cycles per min 
BP: 80/60 mmhg 
Spo2: 99
GRBS:118mg/dl

      Systemic examination:

CVS examination:
S1S2+

Respiratory system examination :
Bilateral Airway E +

Per abdomen examination:
Soft, tender+ right and left hypochondrium and epigastrium, bowel sounds+

CNS:N

Diagnosis:
Pyrexia under evaluation with thrombocytopenia
Acute kidney injury(?acute glomerulonephritis)

USG Abdomen:
Bulky kidney's with raised echogenicity of both kidney's
Mild hepatomegaly 

on22/10/22
On 25/10/22
On 26/10/22

Treatment:
Day-1:
I/U:1000/200ml
BP:100/50mmhg
PR:75bpm
SpO2:97 @RA
Temp:99.3F
CVS:S1S2+
RS:BAE+
P/A:guarding RT HC+, epigastric tenderness
CNS:NFD
1.IV.FLUILDS 2 NS,1RL @100ml/hr
2.T.DOXYCLYINE 100mg PO/BD
3.INJ.MONOCEF 1gm /IV/BD
4.INJ.PAN 40mg/IV/OD
5.I/U CHARTING
6.INJ.ZOFER 4mg/IV/BD
9.T.SPOROLAC/PO/BD
10.INJ.LASIX 20mg/PV/if SBP more than 100mmhg

Day:2: 
ICU bed 4 
24/10/22
Day2
S:
Fever spikes+
Dry cough since night
Decreased urine output
1 episode of vomiting at night
Stools not passed since yesterday 

O:
Pt is C/C/C
BP:120/80mmhg
PR:86bpm
SpO2:98%@RA
RR:21/min
Input/Output:2800ml/200ml
Temp:100F
CVS:S1S2+
RS:BAE+
P/A:soft,NT
CNS: NFD

A:
PYREXIA UNDER EVALUATION WITH THROMBOCYTOPENIA
ACUTE KIDNEY INGURY(?GLOMERULONEPHRITIS)
1.IV FLUIDS 2 NS, 2 RL@100ML/HR
2.T.DOXYCLYINE 100mg PO/BD
3.INJ MONOCEF 1 gm/IV/BD
4.INJ PAN 40 mg/IV/OD
5.T.SPOROLAC/PO/SOS
6.INJ.LASIX 20mg IV if SBP more than 100mmhg
7.PLANNED FOR DIALYSIS 

Day-3
S:
Dialysis done on 24/10/22 @8:30pm to 10:30pm
Fever spikes subsided
1 episode of vomiting at night
Occasionally dry cough

O:
Pt is C/C/C
BP:110/80mmhg
PR:84bpm
SpO2:97%@RA
RR:22/min
Input/Output:1100ml/350ml
Temp:99F
CVS:S1S2+
RS:BAE+
P/A:soft,NT
CNS: NFD
Urine passed 
Stool passed

A:
PYREXIA UNDER EVALUATION WITH THROMBOCYTOPENIA
ACUTE KIDNEY INGURY(?GLOMERULONEPHRITIS)

P:
1.IV FLUIDS 2 NS, 2 RL@100ML/HR
2.T.DOXYCLINE 100mg PO/BD(D3)
3.INJ MONOCEF 1 gm/IV/BD(D3)
4.INJ PAN 40 mg/IV/OD
5.T.SPOROLAC/PO/SOS
6.INJ.LASIX 20mg IV if SBP more than 100mmhg

Day-4
ICU bed 5 
26/10/22
S:
No Fever spikes
No vomitings

O:
Pt is C/C/C
BP:120/70mmhg
PR:84bpm
SpO2:96%@RA
RR:24/min
Temp:98.4F
Input/Output:2600/550ml
CVS:S1S2+
RS:BAE+
P/A:soft,NT
CNS: NFD
Stool passed

A:
PYREXIA UNDER EVALUATION WITH THROMBOCYTOPENIA
ACUTE KIDNEY INGURY(?ACUTE INTERSTITIAL NEPHRITIS)

P:
1.IV FLUIDS 2 NS, 2 RL@100ML/HR
2.T.DOXYCLINE 100mg PO/BD(D4)
3.INJ MONOCEF 1 gm/IV/BD(D4)
4.INJ PAN 40 mg/IV/BD
5.INJ.LASIX 20mg IV if SBP more than 110mmhg

Day-5

27/10/22
No Fever spikes
No vomitings

O:
Pt is C/C/C
BP:110/70mmhg
PR:62bpm
SpO2:94%@RA
RR:24/min
Temp:98.4F
Input/Output:2600/550ml
CVS:S1S2+
RS:BAE+
P/A:soft,NT
CNS: NFD
Stool passed

A:

ACUTE KIDNEY INGURY(?ACUTE INTERSTITIAL NEPHRITIS) 
H/O CANNABIS USE since 6YEARS
H/O ALCOHOLISM since 6 years

P:
1.ORAL FLUIDS 1000ml/Day
2.T.DOXYCLINE 100mg PO/BD(D5)
3.INJ MONOCEF 1 gm/IV/BD(D5)
4.INJ PAN 40 mg/IV/BD
5.INJ.LASIX 20mg IV ifSBP morethan120mmhg
6.SYP. ARISTOZYME 15ml po TID

Day-6

28/10/22
No Fever spikes

O:
Pt is C/C/C
BP:110/70mmhg
PR:68bpm
SpO2:97%@RA
RR:16/min
Temp:98.4F
CVS:S1S2+
RS:BAE+
P/A:soft,NT
CNS: NFD
Stool passed

A:

ACUTE KIDNEY INGURY(?ACUTE INTERSTITIAL NEPHRITIS) 
H/O CANNABIS USE since 6YEARS
H/O ALCOHOLISM since 6 years

P:
1.IVF 2 NS @ 100ml/hr
2.T.DOXYCLINE 100mg PO/BD(D5)
3.INJ MONOCEF 1 gm/IV/BD(D5)
4.TAB.RANTAC150mg po/od
5.INJ.LASIX 20mg IV ifSBP morethan120mmhg
6.SYP. ARISTOZYME 15ml po TID 
7.INJ.ZOFER4mg IV SOS

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